Exchange
From PowerFolder Wiki
Preface
This article describes how to setup PowerFolder Server to send emails via Microsoft Exchange. The SMTP connection can be setup in the Server admin console under Preferences / Mail. Make sure to check "Support for Microsoft Exchange".
SMTP Username
When logging in to Exchange you need to use a username that's more than your simple login name. For example, if your email address is "J.User@server.com", your Windows NT login name is "juser", your NT domain name is "dom", and your Exchange mailbox name is "Joe User", then you would need to use a username of "dom\juser\J.User" when logging in.